On the first floor of the palace, in the so called "golden apartment", used for parties and as princess apartment, the most meaningful works of the art gallery are displayed. In the Art gallery, consisting of works coming from churches in Piacenza as well as from public or private collections, there is a beautiful anthology of paintings witnessing how Piacenza, between 16th, 17th and 18th century, was able to attract artists coming from various cultural contests, taking advantage of its being a junction point between several different types of experience. Visitors may therefore admire paintings by painters from Liguria, namely Domenico Fiasella, known as Sarzana, and Giovanni Battista Merano; from Lombardia, as those by Camillo Boccaccino, Giovanni Battista Trotti, known as Malosso, Carlo Francesco and Giuseppe Nuvolone; from Emilia, like the works by Girolamo Mazzola Bedoli, Giovanni Lanfranco, Pier Francesco Ferrante, Alessandro Tiarini. Not to mention some famous northerners, among whom Justus Susterman, G. Cristoforo Storer, Pieter Bout and Roberto De Longe. One small room is dedicated to the exhibition of Botticelli's TondoMadonna adorante il Bambino con san Giovannino (Madonna adoring Child with Little St. John), a work that is precious both for its formal, aesthetic characteristics and for its content. This work, probably dating back to 1485, is a meaningful example of the style of the famous painter from Tuscany. The gesture of the Child is spontaneous, but at the same time it is a learned reference to the Jewish practice of circumcision. The same capability to conjugate adherence to truth and religious concentration is evident in the Virgin, both for the grace and purity of her face and for the expression of the whole figure, seized in the act of bending the head towards the shoulder, revealing both adoration and a deep commotion.
In the Throne Room there are important works dedicated to the Farnese family, by Brescianino, by Tempesta and two biblical masterpieces by Ilario Spolverini. To him three other rooms are dedicated, where paintings celebrating Elizabeth Farnese (Fasti) are displayed, as well as some battle paintings.
Two small rooms of the Art gallery are dedicated to the last part of the pictorial itinerary in the Gallery, illustrating the shift from the 18th to the 19th century: from "Fasti" and "the age of reason" to romanticism. Gaspare Landi is outstanding: he was a key figure in Italian and Piacenza's art, because he spread the neoclassical style and philosophy and then gradually overcame it through portrait, which became to him the ideal expression of a psychological analysis seizing the time, the society and the anxiety for the arrival of a new time. Two works by his favourite pupil, C. M. Viganoni, and by his nearly pupil L. Toncini end the itinerary.